DIMEO Experience

Life Science

Contents

Corporate Overview

Experience Profile

Services

Corporate Overview

Through three generations of family leadership, the Dimeo organization has successfully nurtured and grown a corporate culture anchored to service, transparency, quality, and superior value. Our Philosophy Builds Success

Steve Rutledge President & CEO

Christopher Doepper Executive Vice President & COO

Brad Dimeo Chairman

Today, the company is led by Stephen F. Rutledge, President & CEO, Bradford S. Dimeo, Chairman and Chris Doepper, Executive Vice President & COO. This leadership team works with our clients and project teams to ensure complete customer satisfaction. At Dimeo, we place significant emphasis on assuring strong team alignment on every project we plan and build.

O We develop and nurture team relationships and collaborations that result in constructing buildings that exceed our clients’ expectations. Brad Dimeo, Chairman

30

A SH

DIMEO CONSTRUCTION COMPANY 4

Our Resources and Market Position

sub contractors >6000 9 DECADES serving clients OSHA BEST IN NATION inspection record among

$ S/W/MBE contracts 1.5 BILLION 265 + PROFESSIONALS average longevity 15+ years

.63 EMR

ranked CM AT RISK ENR TOP

CMAR >85% 8 BIM/VDC experts BILLION $1 bonding financial strengths

$2.7 BILLION LEAN assignments

preconstruction ANNUALLY $2 BILLION

5

Experience Profile

3 million square feet Life Sciences/Research & Development

750 + fume hoods

500,000 square feet

950,000 square feet research and wet lab space (BSL 1,2,3)

450,000 square feet computer labs and clean rooms

75,000 square fee t animal care

academic and teaching space

animal care, insectories, growth chambers, clean rooms, green house aquatics, micro-biology, organic chemistry and physics labs

35 + Highly experienced MEPFP centric,

Life Sciences/R&D professionals in-house

7 Life Sciences

101 College Street // New Haven, CT Size: 500,000 sf // Architect: Elkus-Manfredi Architects Winstanley Enterprises

Dimeo Construction Company recently completed the core and shell of a new 557,585 sf twelve-story office and life sciences research development facility located at 101 College Street in New Haven, CT. The building is designed by Elkus Manfredi Architects and in addition to the new building, will feature a parking area for 116 vehicles, loading docks at service drives, and site improvements, including a semi-public outdoor courtyard, sidewalks, and streetscape improvements.

DIMEO CONSTRUCTION COMPANY 8

9 Major Experience

Rhode Island State Health Lab // Providence, RI Size: 212,000 sf // Architect: HOK Ancora Partners

Construction is underway on the 212,000-square-foot, seven-story development. It will house the state’s new health lab, life sciences labs for Brown University, and additional biotechnology space.

DIMEO CONSTRUCTION COMPANY 10

Office & Lab Fitout // New Haven, CT Size: 60,000 sf // Architect: Elkus Manfredi Architects Alexion

The Alexion tenant fitout of level 7 and partial level 1 at 101 College Street includes approximately 60,000 sf of lab, office and meeting space. Level 1 includes molecular chemistry and a chemical formulation process lab. It also includes collaboration spaces, office spaces, freezer farm, NMR room and shipping/receiving space. Level 7 includes bioanalytical, diagnostics, target validation, and formulations labs. It also includes glasswash and sterilization space, walk-in cold rooms, mass spec suite, tissue culture lab, freezer farm and approximately 5400sft of mixed office/meeting space.

11 Major Experience

STEM Research Center Science One Building // Storrs, CT Size: 180,000 sf // Architect: Payette Architects University of Connecticut

Dimeo Construction Company recently completed the University’s new STEM Research Center, as part of the Northwest Science Quad District. This new campus district houses the expansion of UCONN’s research enterprise in a distinct campus quadrangle. It is designed to meet both the current and future programmatic requirements of the University as it seeks to balance the anticipated rise in student enrollment in STEM programs with future research needs. The building program includes research, teaching, administrative, a clean room, a series of material science specific core labs, a 300-seat auditorium and support spaces. The building has been award LEED Gold.

DIMEO CONSTRUCTION COMPANY 12

13 Major Experience

Office & Lab Fitout // New Haven, CT Size: 38,000 sf // Architect: Gensler BioLabs

Located on the second floor of a mid-rise, state-of-the-art life sciences building, Biolabs welcomes employees, tenants of the building, and visitors via a central grand stair from the main lobby of the building. The space was intentionally designed with the goal of creating an interdisciplinary network, workplace, labs, and social spaces to intermingle companies and facilitate cross collaboration and mentorship among residents of the building. Glass walls between the perimeter workspaces and lab facilities at the core provide transparency while bringing natural light to the deepest reaches of the floor. The fitout included several laboratory spaces with supporting MEPS, office, reception area, conference rooms, and a café.. Common areas and amenities are key to connection, entrepreneurship, and a shared experience of building a company from bench to launch. An open and spacious café.area sparks socialization and provides a central gathering place to host trainings, vendor fairs, and external presentations. Furniture and finishes in calming shades of blue and green, along with natural wood tones, create a cohesive environment. Behind the reception desk, a feature wall designed from test tubes in a gradient of blue to green is a playful homage to the scientific pursuits taking place.

DIMEO CONSTRUCTION COMPANY 14

Animal Care Facility Renovations // Providence, RI Size: 30,000 sf // Architect: Leers Weinzapfel Associates Brown University

This 30,000 sf project consisted of the renovation of existing lab space to create an animal care facility, which included new laboratory, teaching and office space for faculty and researchers. The ACF team is dedicated to providing healthy, well-cared-for animals, which are essential to meaningful research, and maintaining the animal facility for their daily care. The veterinarians are directly responsible for the care and use of animals at all Brown University facilities and provide veterinary services to the area hospitals affiliated with the Brown Medical School. They directly support researchers and students, and as veterinary members of the Institutional Animal Care and Use Committee (IACUC), they review all animal care and use protocols.

15 Life Sciences

Science Building // New Haven, CT Size: 280,000 sf // Architect: Stantec / Pelli Clarke Pelli Architects Yale University

The Yale Science Building is a seven-level structure which includes a rooftop greenhouse, aquatics and insect labs, animal care labs, state-of-the-art imaging technology, quantitative biology center, innovative physics labs, chemical storage, and a 500-seat lecture hall. The structure is home to labs, classrooms, and research support spaces dedicated to understanding the evolution of plants, disease vectors of insects, and atomic, molecular, and optical physics. A primary goal of the project was to eliminate disciplinary silos and encourage collaboration across specialized scientific platforms. Project planning occurred over a 21 month timeline, from design concepts through GMP, including multiple design iterations, environmental impact studies and geometric revisions.

DIMEO CONSTRUCTION COMPANY 16

17 Life Sciences

Clarke Science Building // Providence, RI Size: 60,000 sf // Architect: Brewtser Thornton Group Rhode Island College

This project includes a 40,000 sf renovation to an existing building as well as a 20,000 sf addition. When complete, the Clarke Science Building will provide a new space for the college to align with their future life science, physical science, and technology degree programs.

DIMEO CONSTRUCTION COMPANY 18

Mugar Lab // Boston, MA Size: 4,260 sf // Architect: Goody Clancy & Associates, Inc. Northeastern University

The Mugar Life Sciences Building, one of the oldest science buildings on campus, was constructed in 1941. Its 136,321 GSF is fully occupied and spread over four stories plus a basement. The building contains research and administrative space for the College of Science, Bouvé College of Health Sciences, College of Engineering, the Division of Animal Laboratory and Medicine, and Provost-managed core facilities. The Mugar Lab Renovation East project’s footprint is approximately 4,260 square feet on portions of two floors. The renovated project spaces were a mix of wet and dry spaces, including—but not limited to— laboratory spaces, lab support spaces, write-up/student seating spaces, and storage spaces. Most of the spaces required gut-level renovations. The end users of the renovated spaces are existing research programs engaged in biology, biochemistry, or bioengineering-type work at the Biosafety Level (BSL) 2 or 1 level.

19 Major Experience

Kline Chemistry Laboratory // New Haven, CT Size: 79,000 sf // Architect: HBRA Yale University

The renovations to Yale University’s Kline Chemistry Laboratory created state-of-the-art science research labs. Project scope includes an interior gut renovation of the building to make way for all new labs and lab support areas, chemical storage, new casework, medical gases and 220 fume hoods. Exterior envelope improvements and a new 14,000sf mechanical penthouse on the roof were also included in the project. Energy reduction strategies include the use of high-performance hoods, heat recovery systems and fan-wall technology achieving LEED Gold.

DIMEO CONSTRUCTION COMPANY 20

21 Life Sciences

Cell & Gene Therapy Clinical Manufacturing Expansion // Providence, RI Size: 21,360 sf // Architect: CI Design, Inc. Vertex Pharmaceuticals

Dimeo Construction Company recently completed the Cell & Gene Therapy Clinical Manufacturing Expansion project in Providence, Rhode Island. This project was approached in two parts. The first, to create a new 13,500 sf of new Clinical Manufacturing clean space for cell and gene therapy, including architectural, structural, plumbing, mechanical, and electrical infrastructure upgrades. The second part was the occupied renovation of the existing 4,400 sf of research and development space.

DIMEO CONSTRUCTION COMPANY 22

Sterling Chemistry Laboratory // New Haven, CT Size: 160,000 sf // Architect: Cannon Design Yale University

The Sterling Chemistry Lab project consisted of renovations/addition to a 90,000 sf facility. Scope included demolition and new construction of 75,000 sf of the building inclusive of new roof structure to enclose a lab and teaching spaces. The project provides for new chemistry and biology laboratories as well as Office, Lecturer and support. The project included over 220 fume hoods. The project utilized BIM extensively, and earned LEED Gold certification.

23 Life Sciences

Metcalf Hall, Mind Brain Behavior // Providence, RI Size: 74,500 sf // Architect: Leers Weinzapfel Associates Brown University

Dimeo completed construction management services for the comprehensive renovation to Brown University’s Metcalf Hall administrative science and laboratory building. An outgrowth of Brown University’s Academic Enrichment Initiative, Metcalf Hall now houses the Department of Cognitive and Linguistic Sciences, the Psychology Department, and the administrative offices of the Brain Science Program. Dimeo renovated the existing building on the campus to create dry labs, instructional and teaching labs, faculty and student offices, as well as classroom, conference and public lobby space.

DIMEO CONSTRUCTION COMPANY 24

Our Services

Mitigating Risk Through Innovative Services

LEAN CONSTRUCTION MINIMIZING COSTS, MAXIMIZING VALUE

SAFETY & LOGISTICS SAFETY FIRST, SECOND AND LAST

Dimeo teams apply lean approaches to identify efficient work structuring through combining concurrent activities, utilizing just-in time (jit), prefabrication, and modular production strategies.

Dimeo’s Safety and Loss Control Program has been highly effective in maintaining safe and productive job sites, with extensive recognition and industry leadership.

VDC / BIM A MODEL FOR SUCCESS

QUALITY ASSURANCE / CONTROL MAINTAINING THE HIGHEST STANDARDS

Building Information Modeling (BIM) and Virtual Design and Construction (VDC) are powerful catalysts in supporting continuous collaboration among clients, designers, construction firms, manufacturers, and suppliers.

Dimeo professionals implement a proven QA/QC strategy from the point of inception of a project to achieve the intended quality standard specified.

PLANNING MEASURE TWICE, CUT ONCE

SUSTAINABILITY BUILDING FOR THE FUTURE

Dimeo has long been an industry leading participant in the effort to support and build sustainable buildings.

Dimeo’s preconstruction team focuses on engaging the owner and design team to ensure that project risks are planned for and that the best building investment value is realized.

SOURCING A WEALTH OF KNOWLEDGE & EXPERIENCE

COMMISSIONING CERTIFYING AT EVERY STAGE

Dimeo’s purchasing team serves as an independent resource to our project teams and clients throughout the scope, bid, subcontract award, GMP development process.

Dimeo views the period of substantial completion, commissioning & turnover as the real indicator of how well we perform our duties as your construction manager.

DIMEO CONSTRUCTION COMPANY 26

Dimeo’s virtual design team is leading project teams through application of existing condition surveys, design coordination, prefabrication modularization, logistical planning and as-built documentation.

27 Major Experience

75 Chapman Street Providence, RI 02905 401.781.9800 88 Black Falcon Avenue Suite 307 Boston, MA 02210 617.502.3080 700 State Street Suite 101 New Haven, CT 06511 203.777.5410 www.dimeo.com An Equal Opportunity Employer